Alzheimer's Main Features

Alzheimer's Main Features

Examining these three main features of Alzheimer's disease

The brains of people with Alzheimer's disease have an abundance of two abnormal structures – amyloid plaques and neurofibrillary tangles. These are made of misfolded proteins which can stick together with other misfolded proteins to form insoluble aggregates. If these aggregates build up, they can disrupt cellular communication and metabolism. The third main feature of Alzheimer's is the loss of connections between cells leading to the ill–functioning and death of cells (Institute and Aging, 2011).

Amyloid plaques

These plaques consisting largely of insoluble deposits of a toxic protein peptide called beta–amyloid are found in the spaces between the nerve cells in the brain. Beta amyloid

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