Monday, October 2, 2017

Amyloid Β Precursor Protein Analysis


Amyloid Β Precursor Protein Analysis


Amyloid–β Precursor Protein (APP) is a gene that provides instructions for making a protein called amyloid precursor protein (Andrew, 2009). Amyloid precursor protein is found in several tissues and organs including the brain and the spinal cord––in other words the central nervous system (Andrew, 2009). Some studies suggest that in the brain, APP help direct movement of nerve cells during early development. For instance, APP may be involved in the regulation of synaptogenesis which is the formation of synapses between neurons in the nervous system (Dawkins, 2014).

Additionally, APP is cut by enzymes that create smaller fragments that are often released outside the cell. Some fragments that help play a role in AD are soluble amyloid precursor


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